Collected Literature
2,597 patient Systematic Review – Intradiscal Oxygen-Ozone Safe and Effective
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Citation:
Sconza C, Leonardi G, Kon E, Respizzi S, Massazza G, Marcacci M, Di Matteo B. Oxygen-ozone therapy for the treatment of low back pain: a systematic review of randomized controlled trials. Eur Rev Med Pharmacol Sci. 2021 Oct;25(19):6034-6046. doi: 10.26355/eurrev_202110_26881. PMID: 34661263.
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Patients:
2597
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Design:
Systematic review of ozone-oxygen therapy (OOT) RCTs for low back pain.
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Safety:
No reported adverse events.
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Effectiveness:
9 superior, 3 equivalent to control, 3 not assessed.
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Author Comment:
OOT has proven to be a safe treatment with beneficial effects in pain control and functional recovery at short to medium term follow-up