Collected Literature
Intradiscal Oxygen-Ozone 82%/88% effective over 5/10 years
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Citation:
Buric J, Rigobello L, Hooper D. Five and ten year follow-up on intradiscal ozone injection for disc herniation. Int J Spine Surg. 2014 Dec 1;8:17. doi: 10.14444/1017. PMID: 25694935; PMCID: PMC4325503.
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Patients:
107 @ 5 years, 60 @ 10 years.
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Design:
Retrospective review.
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Safety:
Not reported.
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Effectiveness:
75% of patients were able to avoid surgery, and of the patients that avoided surgery, 82% improved at 5 years, and 88% improved at 10 years. 79% of patients had a reduction in herniation volume and the average reduction was 56%.
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Author Comment:
[Authors] conclude that ozone is safe and effective in approximately 75% of patients with disc herniation and the benefit is maintained through ten years.