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Collected Literature

Intradiscal Oxygen-Ozone Superior to ESI Injections at 12 Months

  • Citation:

    Gallucci M, Limbucci N, Zugaro L, Barile A, Stavroulis E, Ricci A, Galzio R, Masciocchi C. Sciatica: treatment with intradiscal and intraforaminal injections of steroid and oxygen-ozone versus steroid only. Radiology. 2007 Mar;242(3):907-13. doi: 10.1148/radiol.2423051934. Epub 2007 Jan 5. PMID: 17209164.

  • Patients:

    159

  • Design:

    Prospective, double blind, RCT; Ozone + ESI vs ESI alone.

  • Safety:

    No adverse events reported.

  • Effectiveness:

    At 6 months, 74% of patients treated with ozone were rated as a success, with improved ODI, compared to 47% in patients treated with steroid/anesthetic alone (P < .01).

  • Author Comment:

    None.

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